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CXCR7 Recombinant antibody, PBS Only

CXCR7 Uni-rAbTM Recombinant Antibody for WB, IF/ICC, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, IF/ICC, ELISA

Conjugate

Unconjugated

CloneNo.

240842C9

Cat no : 83927-1-PBS

Synonyms

ACKR3, 240842C9, C-X-C chemokine receptor type 7, CMKOR1, Chemokine orphan receptor 1

Validation Data Gallery

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  • Western Blot (WB) analysis of various lysates using CXCR7 Recombinant antibody (83927-1-RR)

    WB analysis using 83927-1-RR (same clone as 83927-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 83927-1-RR (CXCR7 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 83927-1-PBS in a different storage buffer formulation.

  • Immunofluorescence (IF) / fluorescent staining of Jurkat cells using CXCR7 Recombinant antibody (83927-1-RR)

    IF Staining of Jurkat using 83927-1-RR (same clone as 83927-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed Jurkat cells using CXCR7 antibody (83927-1-RR, Clone: 240842C9 ) at dilution of 1:100 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2). This data was developed using the same antibody clone with 83927-1-PBS in a different storage buffer formulation.

Product Information

The immunogen of 83927-1-PBS is CXCR7 Fusion Protein expressed in E. coli.

Tested Reactivity human
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Immunogen CXCR7 fusion protein Ag14247
Full Name chemokine (C-X-C motif) receptor 7
Calculated Molecular Weight 362 aa, 41 kDa
Observed Molecular Weight50 kDa
GenBank Accession NumberBC036661
Gene Symbol CXCR7
Gene ID (NCBI) 57007
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purfication
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

CXCR7 (C-X-C chemokine receptor type 7), also known as RDC1, is a G-protein coupled receptor family member. CXCR7 can bind the chemokines CXCL11 and CXCL12 with high affinity, and it also acts as a coreceptor with CXCR4 for a restricted number of HIV isolates. The expression of CXCR7 has been associated with cardiac development, tumor growth, and progression.