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CUL2 Polyclonal antibody, PBS Only

CUL2 Polyclonal Antibody for WB, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

WB, Indirect ELISA

Conjugate

Unconjugated

Cat no : 30071-1-PBS

Synonyms

Validation Data Gallery

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  • Western Blot (WB) analysis of various lysates using CUL2 Polyclonal antibody (30071-1-AP)

    WB analysis using 30071-1-AP (same clone as 30071-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 30071-1-AP (CUL2 antibody) at dilution of 1:400 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 30071-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of PC-3 cells using CUL2 Polyclonal antibody (30071-1-AP)

    WB analysis of PC-3 using 30071-1-AP (same clone as 30071-1-PBS)

    WB result of CUL2 antibody (30071-1-AP; 1:400; incubated at room temperature for 1.5 hours) with sh-Control and sh-CUL2 transfected PC-3 cells. This data was developed using the same antibody clone with 30071-1-PBS in a different storage buffer formulation.

Product Information

30071-1-PBS targets CUL2 in WB, Indirect ELISA applications and shows reactivity with human, mouse samples.

Tested Reactivity human, mouse
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen CUL2 fusion protein Ag32331
Full Name cullin 2
Calculated Molecular Weight 87 kDa
Observed Molecular Weight 80-87 kDa
GenBank Accession NumberBC009591
Gene Symbol CUL2
Gene ID (NCBI) 8453
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

The cullin family proteins are scaffold proteins for the Ring finger type E3 ligases, participating in the proteolysis through the ubiquitin-proteasome pathway. Humans express seven cullin proteins: CUL1-3, CUL4A, CUL4B, CUL5, and CUL7. Each cullin protein can form an E3 ligase similar to the prototype Ring-type E3 ligase Skp1-CUL1-F-box complex. The Cullin-RING-finger type E3 ligases are important regulators in early embryonic development, as highlighted by genetic studies demonstrating that knock-out of CUL1, CUL3, or CUL4A in mice results in early embryonic lethality.