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CRACR2A Monoclonal antibody, PBS Only

CRACR2A Monoclonal Antibody for WB, IHC, IF/ICC, Indirect ELISA
Cat No. 66787-1-PBS

Host / Isotype

Mouse / IgG1

Reactivity

human

Applications

WB, IHC, IF/ICC, Indirect ELISA

EFCAB4B, EF-hand calcium-binding domain-containing protein 4B, CRAC channel regulator 2A, Calcium release-activated channel regulator 2A, Calcium release-activated calcium channel regulator 2A

Formulation:  PBS Only
PBS and Azide
PBS Only
Conjugate:  Unconjugated
Size/Concentration: 

-/ -

Freight/Packing: -

Quantity

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Product Information

66787-1-PBS targets CRACR2A in WB, IHC, IF/ICC, Indirect ELISA applications and shows reactivity with human samples.

Tested Reactivity human
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Immunogen CRACR2A fusion protein Ag7525 Predict reactive species
Full Name EF-hand calcium binding domain 4B
Calculated Molecular Weight 46 kDa
Observed Molecular Weight 80-90 kDa
GenBank Accession NumberBC004524
Gene Symbol CRACR2A
Gene ID (NCBI) 84766
RRIDAB_2882132
Conjugate Unconjugated
Form Liquid
Purification MethodProtein G purification
UNIPROT IDQ9BSW2
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

CRACR2A (also called CRAC regulator 2A, EFCAB4B) is a cytoplasmic Ca2+ sensor predominantly expressed in lymphocytes. It has two isoforms: a long isoform of CRACR2A-a round 80-90 kDa and a short isoform of CRACR2A-c around 46 kDa. CRACR2A-c is involved in the regulation of Ca2+-NFAT signaling. CRACR2A-a exists in a GTP- and Golgi membrane-bound form in resting T cells, while it is present in subsynaptic vesicles that translocated from the Golgi region to the immunological synapse after ligation of TCRs. This antibody recognizes both of CRACR2A-c and CRACR2A-a.

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