COX7A2L Polyclonal antibody, PBS Only

• Featured Product
• KD/KO Validated

COX7A2L Polyclonal Antibody for WB, IHC, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, IHC, Indirect ELISA

Conjugate

Unconjugated

Cat no : 11416-1-PBS

Synonyms

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Validation Data Gallery

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  WB analysis using 11416-1-AP (same clone as 11416-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 11416-1-AP (COX7A2L antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 11416-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human ovary tumor using 11416-1-AP (same clone as 11416-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human ovary tumor using 11416-1-AP (COX7A2L antibody) at dilution of 1:50 (under 10x lens). This data was developed using the same antibody clone with 11416-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human ovary tumor using 11416-1-AP (same clone as 11416-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human ovary tumor using 11416-1-AP (COX7A2L antibody) at dilution of 1:50 (under 40x lens). This data was developed using the same antibody clone with 11416-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human breast cancer using 11416-1-AP (same clone as 11416-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human breast cancer using 11416-1-AP (COX7A2L antibody) at dilution of 1:50 (under 10x lens). This data was developed using the same antibody clone with 11416-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human breast cancer using 11416-1-AP (same clone as 11416-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human breast cancer using 11416-1-AP (COX7A2L antibody) at dilution of 1:50 (under 40x lens). This data was developed using the same antibody clone with 11416-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human ovary tumor using 11416-1-AP (same clone as 11416-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human ovary tumor using 11416-1-AP (COX7A2L antibody) at dilution of 1:50 (under 10x lens). This data was developed using the same antibody clone with 11416-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human ovary tumor using 11416-1-AP (same clone as 11416-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human ovary tumor using 11416-1-AP (COX7A2L antibody) at dilution of 1:50 (under 40x lens). This data was developed using the same antibody clone with 11416-1-PBS in a different storage buffer formulation.

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Product Information

11416-1-PBS targets COX7A2L in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

• Tested Reactivity: human, mouse, rat
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen: COX7A2L fusion protein Ag1980
• Full Name: cytochrome c oxidase subunit VIIa polypeptide 2 like
• Calculated Molecular Weight: 114 aa, 13 kDa
• Observed Molecular Weight: 14 kDa
• GenBank Accession Number: BC007095
• Gene Symbol: COX7A2L
• Gene ID (NCBI): 9167
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• Storage Buffer: PBS Only
• Storage Conditions: Store at -80°C.

Background Information

Cytochrome c oxidase (COX) is the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. The mitochondrially encoded subunits function in electron transfer, and the nuclear encoded subunits may function in the regulation and assembly of the complex. COX7A2L (cytochrome c oxidase subunit 7A-related protein), also known as COX7AR or COX7RP, is an inner mitochondrial membrane protein. This gene is expressed in all tissues, and upregulated in a breast cancer cell line after estrogen treatment. Recently it was found that DNA methylation of COX7A2L had a significant association with therapy response in patients with breast cancer. In Alzheimer's disease the expression of COX7A2L was reduced.