CLEC2D Polyclonal antibody, PBS Only

• 

  WB analysis using 13188-1-AP (same clone as 13188-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 13188-1-AP (CLEC2D antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 13188-1-PBS in a different storage buffer formulation.

• 

  WB analysis of Jurkat using 13188-1-AP (same clone as 13188-1-PBS)

  Jurkat cells were subjected to SDS PAGE followed by western blot with 13188-1-AP (CLEC2D antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 13188-1-PBS in a different storage buffer formulation.

CLEC2D Polyclonal Antibody for WB, Indirect ELISA

Cat No. 13188-1-PBS

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, Indirect ELISA

Synonyms

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Product Information

13188-1-PBS targets CLEC2D in WB, Indirect ELISA applications and shows reactivity with human samples.

• Tested Reactivity: human
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen: CLEC2D fusion protein Ag3862
• Full Name: C-type lectin domain family 2, member D
• Calculated Molecular Weight: 154 aa, 18 kDa
• Observed Molecular Weight: 33 kDa
• GenBank Accession Number: BC019883
• Gene Symbol: CLEC2D
• Gene ID (NCBI): 29121
• RRID: AB_2877920
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• UNIPROT ID: Q9UHP7
• Storage Buffer: PBS only , pH 7.3
• Storage Conditions: Store at -80°C.

Background Information

CLEC2D (C-type lectin domain family 2 member D), also known as LLT1 (lectin-like transcript 1) or OCIL (Osteoclast inhibitory lectin), is a single-pass type II membrane protein expressed by hematopoietic cells and osteoblasts (PMID: 21930700; 14753741). Its expression was found to be tightly correlated with activation on T cells, NK cells, B cells, and DCs (PMID: 21930700). CLEC2D is a ligand for the human NKR-P1A (CD161) receptor and their interaction differentially regulates NK- and T-cell functions (PMID: 16339513, 16339512). It inhibits the formation and function of osteoclasts and modulates the release of interferon-gamma by human NK cells (PMID:14753741; 20415786).