Product Information
23964-1-PBS targets CLEC14A in WB, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.
Tested Reactivity | human, mouse, rat |
Host / Isotype | Rabbit / IgG |
Class | Polyclonal |
Type | Antibody |
Immunogen | CLEC14A fusion protein Ag21081 Predict reactive species |
Full Name | C-type lectin domain family 14, member A |
Calculated Molecular Weight | 490 aa, 52 kDa |
Observed Molecular Weight | 52 kDa, 100 kDa |
GenBank Accession Number | BC031567 |
Gene Symbol | CLEC14A |
Gene ID (NCBI) | 161198 |
RRID | AB_2879377 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Antigen Affinity purified |
UNIPROT ID | Q86T13 |
Storage Buffer | PBS only , pH 7.3 |
Storage Conditions | Store at -80°C. |
Background Information
CLEC14A is a single-pass type I transmembrane protein whose extracellular domain consists of a C-type lectin-like domain (CTLD), a series of EGF-like domains, and a sushi-like domain (PMID: 23644659). CLEC14A is a member of the C-type lectin domain superfamily that also includes endosialin, thrombomodulin and CD93 (PMID: 16336259). It has been reported that CLEC14A is specifically expressed in endothelial cells and mediates cell to cell adhesion (PMID: 21095181). CLEC14A may be involved in tumor angiogenesis (PMID: 21706054; 23644659).