Product Information
13516-1-PBS targets CHRNA5 in WB, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.
Tested Reactivity | human, mouse, rat |
Host / Isotype | Rabbit / IgG |
Class | Polyclonal |
Type | Antibody |
Immunogen | CHRNA5 fusion protein Ag4447 Predict reactive species |
Full Name | cholinergic receptor, nicotinic, alpha 5 |
Calculated Molecular Weight | 468 aa, 53 kDa |
Observed Molecular Weight | 53 kDa |
GenBank Accession Number | BC033639 |
Gene Symbol | CHRNA5 |
Gene ID (NCBI) | 1138 |
RRID | AB_2080670 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Antigen affinity purification |
UNIPROT ID | P30532 |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. |
Background Information
Nicotinic acetylcholine receptors (nAChRs), such as CHRNA5, are members of a superfamily of ligand-gated ion channels that mediate fast signal transmission at synapses. The nAChRs are thought to be (hetero)pentamers composed of homologous subunits. Variants in the CHRNA5 gene are associated with nicotine dependence and lung cancer risk.