CHRM3 Polyclonal antibody, PBS Only

CHRM3 Polyclonal Antibody for WB, Indirect ELISA
Cat No. 21978-1-PBS

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, Indirect ELISA

Formulation:  PBS Only
PBS and Azide
PBS Only
Conjugate:  Unconjugated
Size/Concentration: 

-/ -

Freight/Packing: -

Quantity

Please visit your regions distributor:


Product Information

21978-1-PBS targets CHRM3 in WB, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Reactivity human, mouse, rat
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen CHRM3 fusion protein Ag17791 Predict reactive species
Full Name cholinergic receptor, muscarinic 3
Calculated Molecular Weight 590 aa, 66 kDa
Observed Molecular Weight60-66 kDa
GenBank Accession NumberBC121026
Gene Symbol CHRM3
Gene ID (NCBI) 1131
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDP20309
Storage Buffer PBS only , pH 7.3
Storage ConditionsStore at -80°C.

Background Information

CHRM3 (M3 muscarinic acetylcholine receptor) is a major player in many kinds of cancer (PMID: 26175851). The expression of muscarinic receptors, mainly the CHRM3, is amplified in several types of tumors, including colon cancer, prostate cancer, endometrial carcinoma, and gastric cancer. Colon cancer overexpresses CHRM3, and post-M3R signaling promotes cell growth via the activation of the epidermal growth factor receptors/ERK and protein kinase C/p38 mitogen-activated protein kinase (MAPK) signaling pathways (PMID: 37744266).

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