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CHMP4C Polyclonal antibody, PBS Only

CHMP4C Polyclonal Antibody for WB, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, Indirect ELISA

Conjugate

Unconjugated

Cat no : 16256-1-PBS

Synonyms

Validation Data Gallery

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  • Western Blot (WB) analysis of various lysates using CHMP4C Polyclonal antibody (16256-1-AP)

    WB analysis using 16256-1-AP (same clone as 16256-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 16256-1-AP (CHMP4C antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 16256-1-PBS in a different storage buffer formulation.

Product Information

16256-1-PBS targets CHMP4C in WB, Indirect ELISA applications and shows reactivity with human samples.

Tested Reactivity human
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen CHMP4C fusion protein Ag9279
Full Name chromatin modifying protein 4C
Calculated Molecular Weight 233 aa, 26 kDa
Observed Molecular Weight35 kDa
GenBank Accession NumberBC014321
Gene Symbol CHMP4C
Gene ID (NCBI) 92421
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

CHMP4C (Charged multivesicular body protein 4c), also known as SHAX3. It is expected to be located in the cytoplasm and membrane, which is expressed in heart, spleen and kidney. CHMP4C is one of the charged multivesicular protein (CHMP), and is involved in the composition of the endosomal sorting complex required for transport III (ESCRT-III), facilitating the necessary separation of daughter cells. CHMP4C has been proposed to be involved in the progression of different carcinomas. The molecular weight of CHMP4C is 26 kDa. Phosphorylated at Ser-210 by AURKB during cytokinesis: together with ZFYVE19/ANCHR, phosphorylated CHMP4C retains abscission-competent VPS4 (VPS4A and/or VPS4B) at the midbody ring until abscission checkpoint signaling is terminated at late cytokinesis.