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CFP Polyclonal antibody, PBS Only

CFP Polyclonal Antibody for WB, IHC, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, IHC, Indirect ELISA

Conjugate

Unconjugated

Cat no : 17192-1-PBS

Synonyms

Validation Data Gallery

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  • Western Blot (WB) analysis of Jurkat cells using CFP Polyclonal antibody (17192-1-AP)

    WB analysis of Jurkat using 17192-1-AP (same clone as 17192-1-PBS)

    Jurkat cells were subjected to SDS PAGE followed by western blot with 17192-1-AP (CFP Antibody) at dilution of 1:300 incubated at 4 degree celsius over night. This data was developed using the same antibody clone with 17192-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of human spleen tissue using CFP Polyclonal antibody (17192-1-AP)

    IHC staining of human spleen using 17192-1-AP (same clone as 17192-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human spleen tissue slide using 17192-1-AP (CFP Antibody) at dilution of 1:50 (under 40x lens). This data was developed using the same antibody clone with 17192-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of human spleen tissue using CFP Polyclonal antibody (17192-1-AP)

    IHC staining of human spleen using 17192-1-AP (same clone as 17192-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human spleen tissue slide using 17192-1-AP (CFP Antibody) at dilution of 1:50 (under 10x lens). This data was developed using the same antibody clone with 17192-1-PBS in a different storage buffer formulation.

Product Information

17192-1-PBS targets CFP in WB, IHC, Indirect ELISA applications and shows reactivity with human samples.

Tested Reactivity human
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen CFP fusion protein Ag9798
Full Name complement factor properdin
Calculated Molecular Weight 469 aa, 51 kDa
Observed Molecular Weight 50 kDa
GenBank Accession NumberBC015756
Gene Symbol CFP
Gene ID (NCBI) 5199
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

CFP, also named as Properdin or CFP, is a 469 amino acid protein, which contains 7 TSP type-1 domains. CFP as secreted protein is a positive regulator of the alternate pathway of complement. It binds to and stabilizes the C3- and C5-convertase enzyme complexes. Properdin deficiency poses a significant risk for severe meningococcal infections (PMID: 22229731). Properdin may be novel biomarker for future risk of type 2 diabetes (PMID: 22338105).