CEA Monoclonal antibody

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  WB analysis of human colon using 60053-1-Ig

  human colon tissue were subjected to SDS PAGE followed by western blot with 60053-1-Ig (CEA antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours.

CEA Monoclonal Antibody for ELISA

Cat No. 60053-1-Ig

Clone No.3D1A6

Host / Isotype

Mouse / IgG2b

Reactivity

human

Applications

ELISA

Synonyms

Carcinoembryonic antigen, CD66e, CEA, CEACAM5, Meconium antigen 100

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Product Information

60053-1-Ig targets CEA in ELISA applications and shows reactivity with human samples.

• Tested Reactivity: human
• Host / Isotype: Mouse / IgG2b
• Class: Monoclonal
• Type: Antibody
• Immunogen: CEA fusion protein Ag0672
• Full Name: carcinoembryonic antigen-related cell adhesion molecule 5
• Calculated Molecular Weight: 77 kDa
• GenBank Accession Number: BC034671
• Gene Symbol: CEA
• Gene ID (NCBI): 1048
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Caprylic Acid/Ammonium Sulfate Precipitation
• UNIPROT ID: P06731
• Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol , pH 7.3
• Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20^oC storage. 20ul sizes contain 0.1% BSA.

Background Information

Carcinoembryonic antigen (CEA), also known as CEACAM5 or CD66e, is a cell surface glycoprotein belonging to the immunoglobulin superfamily, mainly serving as a cell adhesion molecule mediating intercellular contact by both homophilic and heterophilic binding (PMID: 21731662). CEA inhibits anoikis and plays a role in tumorigenesis and metastasis. CEA has been found to be overexpressed in a wide variety of human cancers, including colon, breast, and lung (PMID: 17167768). CEA is a tumor marker and is routinely exploited for diagnosis.