Product Information
83662-7-PBS targets CDK9 in IHC, IF/ICC, ELISA applications and shows reactivity with human samples.
Tested Reactivity | human |
Host / Isotype | Rabbit / IgG |
Class | Recombinant |
Type | Antibody |
Immunogen | CDK9 fusion protein Ag2318 Predict reactive species |
Full Name | cyclin-dependent kinase 9 |
Calculated Molecular Weight | 372 aa, 43 kDa |
Observed Molecular Weight | 38-42 kDa, 55 kDa |
GenBank Accession Number | BC001968 |
Gene Symbol | CDK9 |
Gene ID (NCBI) | 1025 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purfication |
UNIPROT ID | P50750 |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. |
Background Information
CDK9(Cyclin-dependent kinase 9) is a member of the Cdc2-like family of kinases. Its cyclin partners are members of the family of cyclin T (T1, T2a and T2b) and cyclin K. The CDK9/cyclin T complexes appear to be involved in regulating several physiological processes. CDK9 has also been described as the kinase of the TAK complex, which is homologous to the P-TEFb complex and involved in HIV replication. In addition, CDK9 seems to have an anti-apoptotic function in monocytes, that may be related to its control over differentiation of monocytes (PMID: 12432243).