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CD81 Recombinant antibody, PBS Only

CD81 Uni-rAbTM Recombinant Antibody for IF/ICC, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

IF/ICC, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

241722G4

Cat no : 84644-2-PBS

Synonyms

TAPA1, S5.7, CD81 molecule, CD81 antigen, 26 kDa cell surface protein TAPA-1

Validation Data Gallery

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  • Immunofluorescence (IF) / fluorescent staining of Jurkat cells using CD81 Recombinant antibody (84644-2-RR)

    IF Staining of Jurkat using 84644-2-RR (same clone as 84644-2-PBS)

    Immunofluorescent analysis of (4% PFA) fixed Jurkat cells using CD81 antibody (84644-2-RR, Clone: 241722G4 ) at dilution of 1:400 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2). This data was developed using the same antibody clone with 84644-2-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 84644-2-RR

    Affinity and Kinetic Characterization of 84644-2-RR

    Biolayer interferometry (BLl) kinetic assays of 84644-2-RR against Human CD81 were performed. The affinity constant is 0.129 nM.

Product Information

The immunogen of 84644-2-PBS is CD81 Fusion Protein expressed in E. coli.

Tested Reactivity human
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Immunogen Fusion Protein
Full Name CD81 molecule
Calculated Molecular Weight26kDa
GenBank Accession NumberNM_004356.4
Gene Symbol CD81
Gene ID (NCBI) 975
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purfication
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

CD81 (also known as TAPA1or TSPAN28) is a membrane protein of the tetraspanin superfamily, which are characterized by the presence of four conserved transmembrane regions. Many of these members are expressed on leukocytes and have been implicated in signal transduction, cell-cell interactions, and cellular activation and development. CD81 is involved in signal transduction and cell adhesion in the immune system (PMID: 9597125). CD81 has also been identified as an essential receptor for HCV (hepatitis C virus) (PMID: 21428934).