Product Information
82747-4-PBS targets CD79a in WB, Indirect ELISA applications and shows reactivity with human samples.
| Tested Reactivity | human |
| Host / Isotype | Rabbit / IgG |
| Class | Recombinant |
| Type | Antibody |
| Immunogen | CD79a fusion protein Ag17924 Predict reactive species |
| Full Name | CD79a molecule, immunoglobulin-associated alpha |
| Calculated Molecular Weight | 226 aa, 25 kDa |
| Observed Molecular Weight | 40 kDa |
| GenBank Accession Number | BC113733 |
| Gene Symbol | CD79A |
| Gene ID (NCBI) | 973 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Protein A purification |
| UNIPROT ID | P11912 |
| Storage Buffer | PBS Only |
| Storage Conditions | Store at -80°C. |
Background Information
CD79a, also named as B-cell antigen receptor complex-associated protein alpha chain or MB-1 membrane glycoprotein, is a 226 amino acid protein, which contains one ITAM domain and one Ig-like C2-type (immunoglobulin-like) domain. CD79A is expressed in B cells and localizes in the cell membrane. CD79A is required in cooperation with CD79B for initiation of the signal transduction cascade activated by binding of antigen to the B-cell antigen receptor complex (BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. CD79A is also required for BCR surface expression and for efficient differentiation of pro- and pre-B-cells.
