Anti-Human CD70 Rabbit Recombinant Antibody, PBS Only

CD70 {ptg:Brand} Recombinant Antibody for FC
Cat No. 98098-1-PBS
Clone No.241325D8

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

FC

241325D8, CD27 L, CD27 ligand, CD27L, CD27-L

Formulation:  PBS Only
PBS and Azide
PBS Only
Conjugate:  Unconjugated
Size/Concentration: 

-/ -

Freight/Packing: -

Quantity

Please visit your regions distributor:


Product Information

98098-1-PBS targets CD70 in FC applications and shows reactivity with human samples.

Tested Reactivity human
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Immunogen Recombinant Protein Predict reactive species
Full Name CD70 molecule
Calculated Molecular Weight 21 kDa
GenBank Accession NumberBC000725
Gene Symbol CD70
Gene ID (NCBI) 970
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purfication
UNIPROT IDP32970
Storage Buffer PBS only , pH 7.3
Storage ConditionsStore at -80°C.

Background Information

CD70, also known as tumor necrosis factor ligand superfamily member 7 (TNFSF7) or CD27 ligand (CD27L), is a transmembrane protein that plays a significant role in the immune system. It is the unique ligand for CD27, a member of the tumor necrosis factor receptor (TNFR) family, and is transiently upregulated upon stimulation of immune cells. CD70 is expressed on lymphocytes and dendritic cells, and its expression can be regulated by activation signals received via toll-like receptors (TLRs), CD40, and the antigen receptor MHC II. It provides complex and not completely understood signaling for B cell development. CD70 is also expressed on various solid tumors and hematolymphoid malignancies, where it may contribute to a poor prognosis.

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