Mouse CD55 Recombinant antibody, PBS Only

• 

  WB analysis using 84519-4-RR (same clone as 84519-4-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 84519-4-RR (CD55 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84519-4-PBS in a different storage buffer formulation.

CD55 Recombinant Antibody for WB, Indirect ELISA

Cat No. 84519-4-PBS

Clone No.241808C10

Host / Isotype

Rabbit / IgG

Reactivity

mouse

Applications

WB, Indirect ELISA

Synonyms

DAF-GPI, Daf1, Daf, Complement decay-accelerating factor, GPI-anchored, Cd55a

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Product Information

84519-4-PBS targets CD55 in WB, Indirect ELISA applications and shows reactivity with mouse samples.

• Tested Reactivity: mouse
• Host / Isotype: Rabbit / IgG
• Class: Recombinant
• Type: Antibody
• Immunogen: FusionProtein
• Full Name: CD55 antigen
• Calculated Molecular Weight: 43kDa
• Observed Molecular Weight: 58-70 kDa
• GenBank Accession Number: NM_010016.3
• Gene Symbol: CD55
• Gene ID (NCBI): 13136
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purfication
• UNIPROT ID: Q61475
• Storage Buffer: PBS Only
• Storage Conditions: Store at -80°C.

Background Information

CD55, also known as DAF, is a glycosylphosphatidylinositol (GPI)-anchored surface glycoprotein that is widely distributed on blood, stroma, epithelial, and endothelial cells (PMID: 7517044; 29503741). It can also exist as a soluble form in plasma, urine, saliva, tears, and synovial fluids (PMID: 29503741). CD55 is a complement regulatory protein (PMID: 2469439; 7517044). It inhibits formation of the C3 convertases through binding to C3b and C4b. It also binds the alternate pathway convertase C3bBb, the classical pathway convertase and C4b2a to accelerate their decay (PMID: 17289551). CD55 also serves as a receptor for coxsackieviruses B1, B3, and B5 and several enteroviruses (PMID: 7538177; 7517044). The observed molecular weight of mature CD55 varies between 50 to 100 kDa depending on the cell type. Different sizes of CD55 might be caused by alternative splicing or different glycosylation patterns (PMID: 29503741).