Anti-Human CD45RA (HI100), PBS Only
CD45RA Monoclonal Antibody for Indirect ELISA
Host / Isotype
Mouse / IgG2b, kappa
Reactivity
human
Applications
Indirect ELISA
Conjugate
Unconjugated
CloneNo.
HI100
Cat no : 65108-1-PBS
Synonyms
Validation Data Gallery
Product Information
65108-1-PBS targets CD45RA in Indirect ELISA applications and shows reactivity with human samples.
Tested Reactivity | human |
Host / Isotype | Mouse / IgG2b, kappa |
Class | Monoclonal |
Type | Antibody |
Immunogen | N/A |
Full Name | protein tyrosine phosphatase, receptor type, C |
GenBank Accession Number | BC014239 |
Gene Symbol | CD45 |
Gene ID (NCBI) | 5788 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Affinity purification |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. |
Background Information
CD45, also known as protein tyrosine phosphatase, receptor type C, is a type I transmembrane protein expressed on the surface of all haematopoietic cells with the exception of erythrocytes and platelets (PMID: 3489673; 28615666). CD45 is a pan-haematopoietic cell marker and has been shown to be essential for T- and B-cell activation and signalling (PMID: 9429890; 16378097). CD45 exists as multiple isoforms due to alternative splicing of three exons (4, 5, and 6, designated A, B, and C) in the extracellular domain (PMID: 12414720). CD45RA is expressed on naïve T cells, B cells, and monocytes (PMID: 1830500; 14687231).