Anti-Rat CD44 Rabbit Recombinant Antibody, PBS Only

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  FC experiment of rat splenocytes using 98208-1-RR (same clone as 98208-1-PBS)

  1x10^6 rat splenocytes were surface stained with 0.25 ug Anti-Rat CD44 Rabbit Recombinant Antibody (98208-1-RR, Clone: 241648F8) (red) or Rabbit IgG Isotype Control Recombinant Antibody (98136-1-RR, Clone: 240953C9) (blue), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were not fixed. This data was developed using the same antibody clone with 98208-1-PBS in a different storage buffer formulation.

CD44 Uni-rAb^TM Recombinant Antibody for FC

Cat No. 98208-1-PBS

Clone No.241648F8

Host / Isotype

Rabbit / IgG

Reactivity

rat

Applications

FC

Synonyms

Hermes antigen, GP90 lymphocyte homing/adhesion receptor, Extracellular matrix receptor III, ECMR-III, CD44 antigen

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Product Information

98208-1-PBS targets CD44 in FC applications and shows reactivity with rat samples.

• Tested Reactivity: rat
• Host / Isotype: Rabbit / IgG
• Class: Recombinant
• Type: Antibody
• Immunogen: Recombinant protein
• Full Name: Cd44 molecule
• Calculated Molecular Weight: 40 kDa
• GenBank Accession Number: XM_006234631.3
• Gene Symbol: Cd44
• Gene ID (NCBI): 25406
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purfication
• UNIPROT ID: O70509
• Storage Buffer: PBS Only
• Storage Conditions: Store at -80°C.

Background Information

CD44 is a type I transmembrane glycoprotein expressed on embryonic stem cells and in various levels on other cell types including connective tissues and bone marrow. CD44 expression is also upregulated in subpopulations of cancer cells and is recognized as a molecular marker for cancer stem cells (PMID: 29747682). It is a cell-surface receptor that mediates cell-cell and cell-matrix interactions through its affinity for hyaluronic acid (HA) and possibly also through its affinity for other ligands (PMID: 10694938). Adhesion with HA plays an important role in cell migration, tumor growth and progression. CD44 is also involved in lymphocyte activation, recirculation and homing, and in hematopoiesis.