CD226 Monoclonal antibody, PBS Only

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  WB analysis of human peripheral blood platelets using 67653-1-Ig (same clone as 67653-1-PBS)

  human peripheral blood platelets were subjected to SDS PAGE followed by western blot with 67653-1-Ig (CD226 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67653-1-PBS in a different storage buffer formulation.

CD226 Monoclonal Antibody for WB, Indirect ELISA

Cat No. 67653-1-PBS

Clone No.7G7A4

Host / Isotype

Mouse / IgG1

Reactivity

Human

Applications

WB, Indirect ELISA

Synonyms

CD226, CD226 antigen, CD226 molecule, DNAM 1, DNAM1, DNAX accessory molecule 1, PTA1, TLiSA1

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Product Information

67653-1-PBS targets CD226 in WB, Indirect ELISA applications and shows reactivity with Human samples.

• Tested Reactivity: Human
• Host / Isotype: Mouse / IgG1
• Class: Monoclonal
• Type: Antibody
• Immunogen: CD226 fusion protein Ag12403
• Full Name: CD226 molecule
• Calculated Molecular Weight: 336 aa, 39 kDa
• Observed Molecular Weight: 65 kDa
• GenBank Accession Number: BC074787
• Gene Symbol: CD226
• Gene ID (NCBI): 10666
• ENSEMBL Gene ID: ENSG00000150637
• RRID: AB_2882852
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein G purification
• UNIPROT ID: Q15762
• Storage Buffer: PBS Only
• Storage Conditions: Store at -80°C.

Background Information

CD226 (DNAM-1) is a ~65 kDa glycoprotein expressed on the surface of NK cells, platelets, monocytes and a subset of T cells. It is a member of the Ig-superfamily containing 2 Ig-like domains of the V-set. CD226 mediates cellular adhesion of platelets and megakaryocytic cells to vascular endothelial cells. The protein also plays a role in megakaryocytic cell maturation. Interactions of CD226 and its ligands, CD155 and CD112, induce NK and T cell-mediated cytotoxicity and cytokine secretion (PMID: 15039383).