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CD1c Polyclonal antibody, PBS Only

CD1c Polyclonal Antibody for IHC, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

IHC, Indirect ELISA

Conjugate

Unconjugated

Cat no : 28838-1-PBS

Synonyms

Validation Data Gallery

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  • Immunohistochemistry (IHC) staining of human tonsillitis tissue using CD1c Polyclonal antibody (28838-1-AP)

    IHC staining of human tonsillitis using 28838-1-AP (same clone as 28838-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human tonsillitis tissue slide using 28838-1-AP (CD1c antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 28838-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of human tonsillitis tissue using CD1c Polyclonal antibody (28838-1-AP)

    IHC staining of human tonsillitis using 28838-1-AP (same clone as 28838-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human tonsillitis tissue slide using 28838-1-AP (CD1C antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 28838-1-PBS in a different storage buffer formulation.

Product Information

28838-1-PBS targets CD1c in IHC, Indirect ELISA applications and shows reactivity with human samples.

Tested Reactivity human
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen CD1c fusion protein Ag29830
Full Name CD1c molecule
Calculated Molecular Weight 333 aa, 38 kDa
GenBank Accession NumberBC126467
Gene Symbol CD1C
Gene ID (NCBI) 911
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

CD1c molecule (CD1c, also known as R7, CD1, CD1A, and BDCA1) is a member of the CD1 family of transmembrane glycoproteins, which synthesizes in the endoplasmic reticulum and expresses on the monocytes, marginal zone B cells in lymph nodes as well as peripheral blood (PMID: 23468110). The CD1 proteins belong to the family of major histocompatibility complex (MHC) class I-like proteins that present lipid-based antigens to T cells (PMID: 15032598; 23127489). CD1c shows interaction with both αβ or γδ T cells and mediates T cell responses against mycobacterium tuberculosis (PMID: 10727456; 10786796).