Anti-Human CD178 (Fas ligand) (NOK-1) Mouse IgG2a Recombinant Antibody, PBS Only

• 

  FC experiment of Transfected HEK-293T using 65598-1-MR (same clone as 65598-1-PBS)

  1x10^6 HEK-293T cells or CD178 transfected HEK-293T cells were surface stained with 0.25 ug Anti-Human CD178 (Fas ligand) (NOK-1) Mouse IgG2a RecAb (65598-1-MR, Clone: NOK-1) and PE-conjugated Goat Anti-Mouse IgG. Cells were not fixed. This data was developed using the same antibody clone with 65598-1-PBS in a different storage buffer formulation.

• 

  FC experiment of Transfected HEK-293T using 65598-1-MR (same clone as 65598-1-PBS)

  1x10^6 HEK-293T cells or CD178 transfected HEK-293T cells were surface stained with 0.25 ug Anti-Human CD178 (Fas ligand) (NOK-1) Mouse IgG2a RecAb (65598-1-MR, Clone: NOK-1) and PE-conjugated Goat Anti-Mouse IgG (red), or Mouse IgG2a Isotype Control (C1.18.4) (65208-1-Ig, Clone: C1.18.4) (blue). Cells were not fixed. This data was developed using the same antibody clone with 65598-1-PBS in a different storage buffer formulation.

CD178 (Fas ligand) {ptg:Brand} Recombinant Antibody for FC

Cat No. 65598-1-PBS

Clone No.NOK-1

Host / Isotype

Mouse / IgG2a

Reactivity

human

Applications

FC

Synonyms

CD178, Fas ligand, FASLG, CD95-L, CD95L

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Product Information

65598-1-PBS targets CD178 (Fas ligand) in FC applications and shows reactivity with human samples.

• Tested Reactivity: human
• Host / Isotype: Mouse / IgG2a
• Class: Recombinant
• Type: Antibody
• Immunogen: L5178Y mouse T lymphoma cells expressing recombinant human FasL
• Full Name: Fas ligand (TNF superfamily, member 6)
• Calculated Molecular Weight: 281 aa, 31 kDa
• GenBank Accession Number: BC017502
• Gene Symbol: Fas Ligand
• Gene ID (NCBI): 356
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purification
• Storage Buffer: PBS only , pH 7.3
• Storage Conditions: Store at -80°C.

Background Information

CD178, also known as Fas ligand, is a type II transmembrane protein that belongs to the tumor necrosis factor (TNF) family. It is expressed on NK cells, cytotoxic T lymphocytes and activated CD4+ Th1 cells. CD178 transduces apoptotic signal into cells by binding to FAS/CD95. It is involved as a death factor in the regulation of activation-induced cell death, establishment of immune privilege and tumor cell survival.