Anti-Human CD177 Rabbit Recombinant Antibody, PBS Only

CD177 Uni-rAbTM Recombinant Antibody for FC
Cat No. 98086-1-PBS
Clone No.241339F4

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

FC

NB1, Human neutrophil alloantigen 2a, HNA-2a, HNA2A, HNA 2a

Formulation:  PBS Only
PBS and Azide
PBS Only
Conjugate:  Unconjugated
Size/Concentration: 

-/ -

Freight/Packing: -

Quantity

Please visit your regions distributor:


Product Information

98086-1-PBS targets CD177 in FC applications and shows reactivity with human samples.

Tested Reactivity human
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Immunogen Recombinant Protein Predict reactive species
Full Name CD177 molecule
Calculated Molecular Weight 437 aa, 46 kDa
GenBank Accession NumberBC029167
Gene Symbol CD177
Gene ID (NCBI) 57126
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purfication
UNIPROT IDQ8N6Q3
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

CD177, also known as NB1, HNA-2a or PRV-1, is a glycosylphosphatidylinositol (GPI)-anchored glycoprotein that belongs to the uPAR/CD59/Ly6 snake toxin superfamily (PMID: 17898576). It is expressed exclusively by neutrophils, neutrophilic metamyelocytes, and myelocytes (PMID: 17580308). CD177 interacts with β2 integrin CD11b/CD18 and CD11a/CD18, PECAM-1, and participates in neutrophil activation and transmigration (PMID: 17580308; 21193407). CD177 has been identified as a useful biomarker for myeloproliferative diseases (PMID: 17898576).

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