Anti-Human CD13 (WM15)
CD13 Monoclonal Antibody for FC
Host / Isotype
Mouse / IgG1, kappa
Reactivity
human, non-human primates
Applications
FC
Conjugate
Unconjugated
CloneNo.
WM15
Cat no : 65186-1-Ig
Synonyms
Validation Data Gallery
Tested Applications
Positive FC detected in | human PBMCs |
Recommended dilution
Application | Dilution |
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This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, Check data in validation data gallery. |
Product Information
65186-1-Ig targets CD13 in FC applications and shows reactivity with human, non-human primates samples.
Tested Reactivity | human, non-human primates |
Host / Isotype | Mouse / IgG1, kappa |
Class | Monoclonal |
Type | Antibody |
Immunogen | Human AML cells |
Full Name | alanyl (membrane) aminopeptidase |
Calculated Molecular Weight | 110 kDa |
GenBank Accession Number | BC058928 |
Gene Symbol | CD13 |
Gene ID (NCBI) | 290 |
RRID | AB_2918457 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Purified by protein-A affinity chromatography |
Storage Buffer | PBS with 0.09% sodium azide. |
Storage Conditions | Store at 2-8°C. Stable for one year after shipment. |
Background Information
CD13, also named as APN, ANPEP (aminopeptidase N) or PEPN, is belongs to the peptidase M1 family. CD13 is a heavily glycosylated, ~150-240 kDa, type-II membrane, expressed by most cells of myeloid origin including monocytes, macrophages, granulocytes, and their hematopoietic precursors. It is also abundantly expressed in the brush border of epithelial cells from renal proximal tubules and small intestine, in prostatic epithelial cells, in bile duct canaliculi, in mast cells, and, in some cases, in fibroblasts and smooth muscle cells. CD13 is a multifunctional protein and plays varying roles in cell migration, cell proliferation, cell differentiation and so on. CD13 participates in angiogenesis generating and modulating angiogenic signals, and can be a marker of angiogenic vessels. CD13 is also a pan-myeloid marker, present on mature granulocytes and monocytes. (PMID: 8805662, 10098327, 18603472, 18097955, 17897790, 17888402, 21339174)
Protocols
Product Specific Protocols | |
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FC protocol for CD13 antibody 65186-1-Ig | Download protocol |
Standard Protocols | |
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Click here to view our Standard Protocols |