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CCBE1 Polyclonal antibody, PBS Only

CCBE1 Polyclonal Antibody for IHC, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

IHC, Indirect ELISA

Conjugate

Unconjugated

Cat no : 24449-1-PBS

Synonyms

Validation Data Gallery

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  • Immunohistochemistry (IHC) staining of human kidney tissue using CCBE1 Polyclonal antibody (24449-1-AP)

    IHC staining of human kidney using 24449-1-AP (same clone as 24449-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human kidney tissue slide using 24449-1-AP (CCBE1 Antibody) at dilution of 1:200 (under 10x lens). This data was developed using the same antibody clone with 24449-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of human kidney tissue using CCBE1 Polyclonal antibody (24449-1-AP)

    IHC staining of human kidney using 24449-1-AP (same clone as 24449-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human kidney tissue slide using 24449-1-AP (CCBE1 Antibody) at dilution of 1:200 (under 40x lens). This data was developed using the same antibody clone with 24449-1-PBS in a different storage buffer formulation.

Product Information

24449-1-PBS targets CCBE1 in IHC, Indirect ELISA applications and shows reactivity with human samples.

Tested Reactivity human
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen CCBE1 fusion protein Ag19686
Full Name collagen and calcium binding EGF domains 1
Calculated Molecular Weight 406 aa, 44 kDa
GenBank Accession NumberBC046645
Gene Symbol CCBE1
Gene ID (NCBI) 147372
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

CCBE1 (collagen and calcium-binding EGF domain-containing protein 1) is a secreted protein that is indispensible for lymphangiogenesis during development. CCBE1 may be a guidance molecule that regulates lymphangioblast budding and possibly migration (PMID: 19287381). The gene of CCBE1 maps to 18q21.32 and encodes a protein of 44 kDa that contains an EGF-like domain and two collagen-like domains. Mutations in the CCBE1 gene cause Hennekam lymphangiectasia-lymphedema syndrome (PMID: 19935664).