C6orf25 Polyclonal antibody, PBS Only

• 

  WB analysis using 26131-1-AP (same clone as 26131-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 26131-1-AP (C6orf25 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 26131-1-PBS in a different storage buffer formulation.

C6orf25 Polyclonal Antibody for WB, Indirect ELISA

Cat No. 26131-1-PBS

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, Indirect ELISA

Synonyms

---

Product Information

26131-1-PBS targets C6orf25 in WB, Indirect ELISA applications and shows reactivity with human samples.

• Tested Reactivity: human
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen: C6orf25 fusion protein Ag23442
• Full Name: chromosome 6 open reading frame 25
• Observed Molecular Weight: 24-29 kDa
• GenBank Accession Number: BC113719
• Gene Symbol: C6orf25
• Gene ID (NCBI): 80739
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• UNIPROT ID: O95866
• Storage Buffer: PBS only , pH 7.3
• Storage Conditions: Store at -80°C.

Background Information

C6orf25, also called G6B, is an inhibitory receptor expressed on the surface of platelets,and it acts as a critical regulator of hematopoietic lineage differentiation, megakaryocyte function and platelet production (PMID: 17311996; 12665801; 27743390). C6orf25 has seven isoforms. Isoform B is the only isoform to contain both a transmembrane region and 2 immunoreceptor tyrosine-based inhibitor motifs (ITIMs) and, thus, the only one which probably has a role of inhibitory receptor. Isoform A may be the activating counterpart of isoform B (PMID: 11544253).