Product Information
24459-1-PBS targets C10orf67 in WB, Indirect ELISA applications and shows reactivity with human samples.
Tested Reactivity | human |
Host / Isotype | Rabbit / IgG |
Class | Polyclonal |
Type | Antibody |
Immunogen | C10orf67 fusion protein Ag21465 Predict reactive species |
Full Name | chromosome 10 open reading frame 67 |
Calculated Molecular Weight | 184 aa, 21 kDa |
Observed Molecular Weight | 18-21 kDa |
GenBank Accession Number | BC035732 |
Gene Symbol | C10orf67 |
Gene ID (NCBI) | 256815 |
RRID | AB_2879558 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Antigen affinity purification |
UNIPROT ID | Q8IYJ2 |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. |
Background Information
RNF17 also termed as ring finger protein 17 is a 1623 amino acid protein, which contains 1 ring type zinc finger and 4 tudor domains. RNF17 is specifically expressed in testis. The RING finger motif presents in many ubiquitin E3 ligases. RNF17 interacts with all four members of the Mad family (Mad1, Mxi1, Mad3 and Mad4), which are basic-helix-loop-helix-leucine zipper transcription factors of the Myc oncoprotein network. RNF17 is component of the tectonic-like complex, which is required for ciliogenesis and sonic hedgehog/SHH signaling. RNF17 is able to form dimers or polymers both in vitro and in vivo, indicating that it may play a role in the assembly of RNF17 granules. RNF17 encodes a novel key regulator of spermiogenesis.