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BZRAP1 Polyclonal antibody, PBS Only

BZRAP1 Polyclonal Antibody for WB, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

WB, Indirect ELISA

Conjugate

Unconjugated

Cat no : 28241-1-PBS

Synonyms

Validation Data Gallery

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  • Western Blot (WB) analysis of Neuro-2a cells using BZRAP1 Polyclonal antibody (28241-1-AP)

    WB analysis of Neuro-2a using 28241-1-AP (same clone as 28241-1-PBS)

    Neuro-2a cells were subjected to SDS PAGE followed by western blot with 28241-1-AP (BZRAP1 antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 28241-1-PBS in a different storage buffer formulation.

Product Information

28241-1-PBS targets BZRAP1 in WB, Indirect ELISA applications and shows reactivity with human, mouse samples.

Tested Reactivity human, mouse
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen BZRAP1 fusion protein Ag28198
Full Name benzodiazapine receptor (peripheral) associated protein 1
Calculated Molecular Weight 1857 aa, 200 kDa
Observed Molecular Weight 200-235 kDa
GenBank Accession NumberBC146852
Gene Symbol BZRAP1
Gene ID (NCBI) 9256
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

BZRAP1, also named as TSPOAP1 and PBR-associated protein 1 (PRAX-1), is a cytoplasmic protein of 1857 residues. It plays a key role in inflammation, neuroinflammation, mental and metabolic diseases, and cancer. BZRAP1 predominantly expressed in the central nervous system, pituitary gland, and thymus, specially abundant in the CA1 subfield of the hippocampus. Tumor necrosis factor receptor 1 (TNFR1), vascular cell adhesion molecule 1 (VCAM1), cyclic AMP response element-binding protein 1 (CREB1), T-cell receptor (TCR), nucleotide-binding oligomerization domain, leucine-rich repeat and pyrin domain containing 3 (NLRP3), DNA-dependent protein kinase (DNA-PK or PRKDC), and mitochondrial permeability transition pore (mPTP) were the major interaction partners of BZRAP1 (PMID: 34212002).