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  • KD/KO Validated

BBS5 Polyclonal antibody

BBS5 Polyclonal Antibody for IHC, IP, WB,ELISA

Host / Isotype

Rabbit / IgG


human, mouse, rat





Cat no : 14569-1-AP


Bardet Biedl syndrome 5, BBS5

Tested Applications

Positive WB detected inmouse retina tissue, mouse testis tissue, human testis tissue, rat testis tissue, mouse eye tissue
Positive IP detected inmouse testis tissue
Positive IHC detected inhuman testis tissue, mouse kidney tissue, human stomach tissue, human kidney tissue, mouse testis tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0

Recommended dilution

Western Blot (WB)WB : 1:500-1:1000
Immunoprecipitation (IP)IP : 0.5-4.0 ug for IP and 1:500-1:1000 for WB
Immunohistochemistry (IHC)IHC : 1:50-1:500
Sample-dependent, check data in validation data gallery

Product Information

14569-1-AP targets BBS5 in WB, IP, IHC, IF,ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Reactivity human, mouse, rat
Cited Reactivityhuman, mouse, rat
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen BBS5 fusion protein Ag6153
Full Name Bardet-Biedl syndrome 5
Calculated molecular weight 39 kDa
Observed molecular weight 39 kDa
GenBank accession numberBC044593
Gene symbol BBS5
Gene ID (NCBI) 129880
Conjugate Unconjugated
Form Liquid
Purification Method Antigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Background Information

BBS5 encodes a protein that has been directly linked to Bardet-Biedl syndrome. Bardet-Biedl syndrome (BBS) is an autosomal recessive condition characterised by rod-cone dystrophy, postaxial polydactyly, central obesity, mental retardation, hypogonadism, and renal dysfunction. Other associated clinical findings in BBS patients include diabetes, hypertension and congenital heart defects. BBS expression varies both within and between families and diagnosis is often difficult. Experimentation in non-human eukaryotes suggests that BBS5 is expressed in ciliated cells and that it is required for the formation of cilia. Alternate transcriptional splice variants have been observed but have not been fully characterized.


Product Specific Protocols
WB protocol for BBS5 antibody 14569-1-APDownload protocol
IHC protocol for BBS5 antibody 14569-1-APDownload protocol
IP protocol for BBS5 antibody 14569-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols



PLoS Biol

Loss of Bardet-Biedl syndrome proteins causes synaptic aberrations in principal neurons.

Authors - Naila Haq
  • KO Validated

Cell Rep

FBF1 deficiency promotes beiging and healthy expansion of white adipose tissue.

Authors - Yingyi Zhang

Nephrology (Carlton)

Visualizing renal primary cilia.

Authors - James A Deane

Invest Ophthalmol Vis Sci

Essential Role of the Chaperonin CCT in Rod Outer Segment Biogenesis.

Authors - Satyabrata Sinha
humanIF, WB

J Biol Chem

The BBSome assembly is spatially controlled by BBS1 and BBS4 in human cells.

Authors - Avishek Prasai

J Biol Chem

DAZ interacting protein 1 (Dzip1) phosphorylation by Polo-like kinase 1 (Plk1) regulates the centriolar satellites localization of the BBSome during the cell cycle.

Authors - Boyan Zhang