BAK Polyclonal antibody
BAK Polyclonal Antibody for ELISA
Host / Isotype
Rabbit / IgG
human, mouse, rat and More (1)
WB, IHC, IF, ELISA
Cat no : 14673-1-AP
|Sample-dependent, check data in validation data gallery|
|WB||See 31 publications below|
|IHC||See 2 publications below|
|IF||See 1 publications below|
14673-1-AP targets BAK in WB, IHC, IF, ELISA applications and shows reactivity with human, mouse, rat samples.
|Tested Reactivity||human, mouse, rat|
|Cited Reactivity||human, mouse, rat, sheep|
|Host / Isotype||Rabbit / IgG|
|Immunogen||BAK fusion protein Ag6354|
|Full Name||BCL2-antagonist/killer 1|
|Calculated molecular weight||23 kDa|
|GenBank accession number||BC004431|
|Gene ID (NCBI)||578|
|Purification Method||Antigen affinity purification|
|Storage Buffer||PBS with 0.02% sodium azide and 50% glycerol pH 7.3.|
|Storage Conditions||Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.|
BAK1, also named as BAK, BCL2L7 and CDN1, belongs to the Bcl-2 family. In the presence of an appropriate stimulus, BAK1 accelerates programmed cell death by binding to, and antagonizing the anti-apoptotic action of BCL2 or its adenovirus homolog E1B 19k protein. Low micromolar levels of zinc ions inhibit the promotion of apoptosis. (PMID:17157251) BAK1 gene product primarily enhances apoptotic cell death following an appropriate stimulus. It can inhibit cell death in an Epstein-Barr virus-transformed cell line.
Mitochondrial membrane proteins and VPS35 orchestrate selective removal of mtDNA
By reducing hexokinase 2, resveratrol induces apoptosis in HCC cells addicted to aerobic glycolysis and inhibits tumor growth in mice.
Mol Ther Nucleic Acids
lncRNA MIRF Promotes Cardiac Apoptosis through the miR-26a-Bak1 Axis.
J Proteome Res
PPE38 of Mycobacterium marinum triggers the cross-talk of multiple pathways involved in the host response, as revealed by subcellular quantitative proteomics.
alpha-Bisabolol induces dose- and time-dependent apoptosis in HepG2 cells via a Fas- and mitochondrial-related pathway, involves p53 and NFkappaB.
Dioscin, a natural steroid saponin, shows remarkable protective effect against acetaminophen-induced liver damage in vitro and in vivo.