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BAG1L-specific Polyclonal antibody, PBS Only

BAG1L-specific Polyclonal Antibody for IF/ICC, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

IF/ICC, Indirect ELISA

Conjugate

Unconjugated

Cat no : 16148-1-PBS

Synonyms

Validation Data Gallery

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  • Immunofluorescence (IF) / fluorescent staining of HepG2 cells using BAG1L-specific Polyclonal antibody (16148-1-AP)

    IF Staining of HepG2 using 16148-1-AP (same clone as 16148-1-PBS)

    Immunofluorescent analysis of HepG2 cells, using BAG1 antibody 16148-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red). This data was developed using the same antibody clone with 16148-1-PBS in a different storage buffer formulation.

Product Information

16148-1-PBS targets BAG1L-specific in IF/ICC, Indirect ELISA applications and shows reactivity with human samples.

Tested Reactivity human
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen Peptide
Full Name BCL2-associated athanogene
Calculated Molecular Weight 39 kDa
GenBank Accession NumberNM_004323
Gene Symbol BAG1
Gene ID (NCBI) 573
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

BAG1 has been identified that modulates gene transcription through poorly defined mechanisms. Four isoforms of the BAG1 protein (BAG1S, BAG1, BAG1M, and BAG1L) can be produced from a common mRNA by use of alternative translation initiation sites, including a non-canonical CTG codon in one instance. The longest, BAG1L (Mr ~50K), contains a nuclear localization signal (NLS) and resides in the nucleus, whereas BAG1M (Mr ~46K) has an incomplete NLS and distributes mainly in cytosol, unless dragged into the nucleus through interactions with other. Distribution of BAG1S(p33) is not clear yet. This antibody can recognize BAG1L and BAG1V.