BACE2 Polyclonal antibody

BACE2 Polyclonal Antibody for WB, IHC, ELISA

Host / Isotype

Rabbit / IgG


human, mouse, rat





Cat no : 16321-1-AP


AEPLC, ALP56, Asp 1, ASP1, ASP21, Aspartic like protease 56 kDa, Aspartyl protease 1, BACE2, BAE2, Beta secretase 2, CDA13, CEAP1, Down region aspartic protease, DRAP, Memapsin 1, Theta secretase, UNQ418/PRO852

Tested Applications

Positive WB detected inHEK-293 cells, Hela cells, SH-SY5Y cells
Positive IHC detected inhuman colon cancer tissue, human breast cancer tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0

Recommended dilution

Western Blot (WB)WB : 1:500-1:1000
Immunohistochemistry (IHC)IHC : 1:50-1:500
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Published Applications

WBSee 2 publications below

Product Information

16321-1-AP targets BACE2 in WB, IHC, ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Reactivity human, mouse, rat
Cited Reactivityhuman, mouse
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen BACE2 fusion protein Ag9404
Full Name beta-site APP-cleaving enzyme 2
Calculated Molecular Weight 518 aa, 56 kDa
Observed Molecular Weight 60 kDa
GenBank Accession NumberBC014453
Gene Symbol BACE2
Gene ID (NCBI) 25825
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.


Product Specific Protocols
WB protocol for BACE2 antibody 16321-1-APDownload protocol
IHC protocol for BACE2 antibody 16321-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols



Brain Behav Immun

Elevated β-secretase 1 expression mediates CD4+ T cell dysfunction via PGE2 signalling in Alzheimer's disease.

Authors - Linbin Dai

Int J Neurosci

Activating transcription factor 6 reduces Aβ1-42 and restores memory in Alzheimer's disease model mice.

Authors - Yayun Du