B4GALT7 Polyclonal antibody

• Featured Product
• KD/KO Validated

B4GALT7 Polyclonal Antibody for ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, ELISA

Conjugate

Unconjugated

Publications

1

Cat no : 10535-1-AP

Synonyms

B4GAL T7, B4GALT7, Beta 1,4 GalTase 7, beta4Gal T7, XGALT 1, XGALT1, XGPT, XGPT1

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Validation Data Gallery

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  WB analysis using 10535-1-AP

  Various lysates were subjected to SDS PAGE followed by western blot with 10535-1-AP (B4GALT7 antibody) at dilution of 1:800 incubated at room temperature for 1.5 hours.

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Published Applications

• KD/KO: See 1 publications below
• WB: See 1 publications below

Product Information

10535-1-AP targets B4GALT7 in WB, ELISA applications and shows reactivity with human samples.

• Tested Reactivity: human
• Cited Reactivity: human
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen: B4GALT7 fusion protein Ag0793
• Full Name: xylosylprotein beta 1,4-galactosyltransferase, polypeptide 7 (galactosyltransferase I)
• Calculated Molecular Weight: 37 kDa
• Observed Molecular Weight: 37 kDa
• GenBank Accession Number: BC007317
• Gene Symbol: B4GALT7
• Gene ID (NCBI): 11285
• RRID: AB_2274457
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
• Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20^oC storage. 20ul sizes contain 0.1% BSA.

Background Information

B4GALT7 (Beta-1,4-galactosyltransferase 7), also known as galactosyltransferase I, is involved in the formation of proteoglycans which are components of the extracellular matrix in connective tissues (PubMed: 10438455). The reduced activity of B4GALT7 results in delayed wound repair, altered migration, adhesion and contractility of patient fibroblasts (PMID: 16583246, PMID: 18158310). Mutations in B4GALT7 that also result in Spondylodysplastic (PMID: 24755949, PMID: 12417421).

Publications

Species	Application	Title
human	WB	Eur J Hum Genet; Impairment of glycosaminoglycan synthesis in mucopolysaccharidosis type IIIA cells by using siRNA: a potential therapeutic approach for Sanfilippo disease.; Authors - Dziedzic Dariusz D ; KD Validated