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Alix Monoclonal antibody, PBS Only

Alix Monoclonal Antibody for WB, IHC, IF/ICC, Indirect ELISA
Cat No. 67715-1-PBS
Clone No.1H9D9

Host / Isotype

Mouse / IgG1

Reactivity

human, mouse, rat

Applications

WB, IHC, IF/ICC, Indirect ELISA

PDCD6IP, Hp95, DRIP4, ALG-2-interacting protein X, ALG-2-interacting protein 1

Formulation:  PBS Only
PBS and Azide
PBS Only
Conjugate:  Unconjugated
Size/Concentration: 

-/ -

Freight/Packing: -

Quantity

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Product Information

67715-1-PBS targets Alix in WB, IHC, IF/ICC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Reactivity human, mouse, rat
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Immunogen Alix fusion protein Ag30437 Predict reactive species
Full Name programmed cell death 6 interacting protein
Calculated Molecular Weight 868 aa, 96 kDa
Observed Molecular Weight100 kDa
GenBank Accession NumberBC020066
Gene Symbol Alix
Gene ID (NCBI) 10015
RRIDAB_2882905
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDQ8WUM4
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

ALG-2-interacting protein 1 (ALIX), also known as AIP1 or Hp95, is encoded by PDCD6IP gene and is involved in cell death through mechanisms involving its binding partner ALG-2 (apoptosis-linked gene-2). ALG-2 is a 22-kDa protein containing five serially repetitive EF-hand structures and is defined as a regulator of calcium-induced apoptosis following endoplasmic reticulum (ER) stress. ALIX interacts with ALG-2 through its C-terminal proline-rich region and participates in formation of multivesicular bodies. Recent finding suggest that ALIX is a critical component of caspase 9 activation and apoptosis triggered by calcium.

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