Product Information
82906-1-PBS targets AURKA in WB, IF/ICC, Indirect ELISA applications and shows reactivity with human samples.
Tested Reactivity | human |
Host / Isotype | Rabbit / IgG |
Class | Recombinant |
Type | Antibody |
Immunogen | AURKA fusion protein Ag0362 Predict reactive species |
Full Name | aurora kinase A |
Calculated Molecular Weight | 46 kDa |
Observed Molecular Weight | 46 kDa |
GenBank Accession Number | BC002499 |
Gene Symbol | AURKA |
Gene ID (NCBI) | 6790 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purification |
UNIPROT ID | O14965 |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. |
Background Information
AURKA(Aurora kinase A), also named as STK6, STK15 or AIK, belongs to the Ser/Thr protein kinase family. This protein may play a role in cell cycle regulation during anaphase and/or telophase by being involved in microtubule formation and/or stabilization. Some recent evidence revealed that AURKA may also be implicated in tumor development and progression. AURKA is expressed highly in testis and various proliferating cells, migrating as a 46 kDa protein in SDS PAGE.Nuclear staining for AURKA is weak or nonexistent in normal tissue but strong in tumor tissue(PMID:19107951).