ATP6 Monoclonal antibody, PBS Only

ATP6 Monoclonal Antibody for WB, Indirect ELISA

Host / Isotype

Mouse / IgG1

Reactivity

Human, Rat

Applications

WB, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

1H4G5

Cat no : 68442-1-PBS

Synonyms

ATP synthase subunit a, ATP6, ATPASE6, F ATPase protein 6, MT ATP6, MTATP6

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Validation Data Gallery

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  WB analysis using 68442-1-Ig (same clone as 68442-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 68442-1-Ig (ATP6 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68442-1-PBS in a different storage buffer formulation.

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Product Information

68442-1-PBS targets ATP6 in WB, Indirect ELISA applications and shows reactivity with Human, Rat samples.

• Tested Reactivity: Human, Rat
• Host / Isotype: Mouse / IgG1
• Class: Monoclonal
• Type: Antibody
• Immunogen: ATP6 fusion protein Ag31940
• Full Name: ATP synthase 6; ATPase subunit 6
• Calculated Molecular Weight: 25 kDa
• Observed Molecular Weight: 25-30 kDa
• GenBank Accession Number: YP_003024031
• Gene Symbol: ATP6
• Gene ID (NCBI): 4508
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein G purification
• Storage Buffer: PBS Only
• Storage Conditions: Store at -80°C.

Background Information

ATP synthase, also known as FoF1 complex, is a critical mitochondrial OXPHOS enzyme involved in the regulation of mitochondrial ATP production and in the maintenance of the mitochondrial membrane potential. It is composed of three components (F1, Fo and the peripheral stalk). F1, the soluble catalytic core, is above the membrane, inside the matrix of the mitochondria; consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon); Fo, comprising the proton channel, is within the membrane; Fo seems to have nine subunits (a, b, c, d, e, f, g, F6 and 8). ATP6 is the a subunit of Fo region.