ATL3 Recombinant antibody, PBS Only

ATL3 Uni-rAb^TM Recombinant Antibody for WB, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

241937G3

Cat no : 84578-3-PBS

Synonyms

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Validation Data Gallery

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  WB analysis using 84578-3-RR (same clone as 84578-3-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 84578-3-RR (ATL3 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84578-3-PBS in a different storage buffer formulation.

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Product Information

The immunogen of 84578-3-PBS is ATL3 Fusion Protein expressed in E. coli.

• Tested Reactivity: human
• Host / Isotype: Rabbit / IgG
• Class: Recombinant
• Type: Antibody
• Immunogen: ATL3 fusion protein Ag10248
• Full Name: atlastin GTPase 3
• Calculated Molecular Weight: 541 aa, 61 kDa
• Observed Molecular Weight: 58-61 kDa
• GenBank Accession Number: BC077727
• Gene Symbol: ATL3
• Gene ID (NCBI): 25923
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purfication
• Storage Buffer: PBS Only
• Storage Conditions: Store at -80°C.

Background Information

ATL3, belonging to a class of dynamin-like GTPase, was reported to mediate ER fusion. ATL3 is required for the proper formation of the network of interconnected tubules of the endoplasmic reticulum. ATL3 functions as a receptor for ER-phagy, promoting tubular ER degradation upon starvation. Mutations in this gene may be associated with hereditary sensory neuropathy type IF.