ATL3 Recombinant antibody, PBS Only

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  WB analysis using 84578-3-RR (same clone as 84578-3-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 84578-3-RR (ATL3 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84578-3-PBS in a different storage buffer formulation.

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  Affinity and Kinetic Characterization of 84578-3-RR

  Biolayer interferometry (BLl) kinetic assays of 84578-3-RR against Human ATL3 were performed. The affinity constant is 1.14 nM.

ATL3 Uni-rAb^TM Recombinant Antibody for WB, Indirect ELISA

Cat No. 84578-3-PBS

Clone No.241937G3

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, Indirect ELISA

Synonyms

EC:3.6.5.-, Atlastin-3, Atlastin 3, 241937G3

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Product Information

84578-3-PBS targets ATL3 in WB, Indirect ELISA applications and shows reactivity with human samples.

• Tested Reactivity: human
• Host / Isotype: Rabbit / IgG
• Class: Recombinant
• Type: Antibody
• Immunogen: ATL3 fusion protein Ag10248
• Full Name: atlastin GTPase 3
• Calculated Molecular Weight: 541 aa, 61 kDa
• Observed Molecular Weight: 58-61 kDa
• GenBank Accession Number: BC077727
• Gene Symbol: ATL3
• Gene ID (NCBI): 25923
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purfication
• UNIPROT ID: Q6DD88
• Storage Buffer: PBS Only
• Storage Conditions: Store at -80°C.

Background Information

ATL3, belonging to a class of dynamin-like GTPase, was reported to mediate ER fusion. ATL3 is required for the proper formation of the network of interconnected tubules of the endoplasmic reticulum. ATL3 functions as a receptor for ER-phagy, promoting tubular ER degradation upon starvation. Mutations in this gene may be associated with hereditary sensory neuropathy type IF.