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ATL3 Recombinant antibody, PBS Only

ATL3 Uni-rAbTM Recombinant Antibody for WB, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

241937G3

Cat no : 84578-3-PBS

Synonyms

EC:3.6.5.-, Atlastin-3, Atlastin 3, 241937G3

Validation Data Gallery

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  • Western Blot (WB) analysis of various lysates using ATL3 Recombinant antibody (84578-3-RR)

    WB analysis using 84578-3-RR (same clone as 84578-3-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 84578-3-RR (ATL3 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84578-3-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 84578-3-RR

    Affinity and Kinetic Characterization of 84578-3-RR

    Biolayer interferometry (BLl) kinetic assays of 84578-3-RR against Human ATL3 were performed. The affinity constant is 1.14 nM.

Product Information

84578-3-PBS targets ATL3 in WB, Indirect ELISA applications and shows reactivity with human samples.

Tested Reactivity human
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Immunogen ATL3 fusion protein Ag10248
Full Name atlastin GTPase 3
Calculated Molecular Weight 541 aa, 61 kDa
Observed Molecular Weight 58-61 kDa
GenBank Accession NumberBC077727
Gene Symbol ATL3
Gene ID (NCBI) 25923
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purfication
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

ATL3, belonging to a class of dynamin-like GTPase, was reported to mediate ER fusion. ATL3 is required for the proper formation of the network of interconnected tubules of the endoplasmic reticulum. ATL3 functions as a receptor for ER-phagy, promoting tubular ER degradation upon starvation. Mutations in this gene may be associated with hereditary sensory neuropathy type IF.