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ARAP3 Polyclonal antibody, PBS Only

ARAP3 Polyclonal Antibody for IHC, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

IHC, Indirect ELISA

Conjugate

Unconjugated

Cat no : 22578-1-PBS

Synonyms

Validation Data Gallery

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  • Immunohistochemistry (IHC) staining of human colon tissue using ARAP3 Polyclonal antibody (22578-1-AP)

    IHC staining of human colon using 22578-1-AP (same clone as 22578-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human colon tissue slide using 22578-1-AP (ARAP3 Antibody) at dilution of 1:50 (under 40x lens). This data was developed using the same antibody clone with 22578-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of human colon cancer tissue using ARAP3 Polyclonal antibody (22578-1-AP)

    IHC staining of human colon cancer using 22578-1-AP (same clone as 22578-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human colon cancer tissue slide using 22578-1-AP (ARAP3 Antibody) at dilution of 1:50 (under 40x lens). This data was developed using the same antibody clone with 22578-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of human colon tissue using ARAP3 Polyclonal antibody (22578-1-AP)

    IHC staining of human colon using 22578-1-AP (same clone as 22578-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human colon tissue slide using 22578-1-AP (ARAP3 Antibody) at dilution of 1:50 (under 10x lens). This data was developed using the same antibody clone with 22578-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of human colon cancer tissue using ARAP3 Polyclonal antibody (22578-1-AP)

    IHC staining of human colon cancer using 22578-1-AP (same clone as 22578-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human colon cancer tissue slide using 22578-1-AP (ARAP3 Antibody) at dilution of 1:50 (under 10x lens). This data was developed using the same antibody clone with 22578-1-PBS in a different storage buffer formulation.

Product Information

22578-1-PBS targets ARAP3 in IHC, Indirect ELISA applications and shows reactivity with human samples.

Tested Reactivity human
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen ARAP3 fusion protein Ag17436
Full Name ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
Calculated Molecular Weight 1544 aa, 170 kDa
GenBank Accession NumberBC009968
Gene Symbol ARAP3
Gene ID (NCBI) 64411
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

The ADP-ribosylation factor (ARF) family of small GTP-binding proteins are involved in vesicular transport regulation and in controlling cytoskeletal organization and cell adhesion. These proteins are best characterized as regulators of membrane traffic. The Centaurin GTPase-activating protein family comprise a subset of ARF regulatory molecules that transduce PI 3-kinase activation into coordinated control of ARF-dependent pathways. ARAP3 (Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3) is unique for its dual specificity GAPs (GTPase activating protein) activity for Arf6 (ADP-ribosylation factor 6) and RhoA (Ras homolog gene family member A) regulated by PtdIns(3,4,5)P3 (phosphatidylinositol (3,4,5)-trisphosphate) and a small GTPase Rap1-GTP and is involved in regulation of cell shape and adhesion.