Product Information
16709-1-AP targets Angiogenin in ELISA applications and shows reactivity with human samples.
| Tested Reactivity | human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Angiogenin fusion protein Ag10120 Predict reactive species |
| Full Name | angiogenin, ribonuclease, RNase A family, 5 |
| Calculated Molecular Weight | 147 aa, 17 kDa |
| GenBank Accession Number | BC054880 |
| Gene Symbol | Angiogenin |
| Gene ID (NCBI) | 283 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | P03950 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol , pH 7.3 |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA. |
Background Information
Angiogenin (ANG), a angiogenic ribonuclease, is a member of the vertebrate-specific, secreted RNASE superfamily. Angiogenin, originally identified as a tumor angiogenic factor, was related with the growth and metastasis of numerous tumors. Angiogenin is also a component of normal human plasma and follicular Xuid. Its widespread expression in human tissues suggests angiogenin may have biological functions in addition to the promotion of angiogenesis. Recently, its biological activity has been extended to stimulating cell proliferation and promoting cell survival. It is a 17 kDa precursor which is cleaved to generate the 14 kDa mature protein.
