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AKNA Polyclonal antibody, PBS Only

AKNA Polyclonal Antibody for WB, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, Indirect ELISA

Conjugate

Unconjugated

Cat no : 23785-1-PBS

Synonyms

Validation Data Gallery

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  • Western Blot (WB) analysis of K-562 cells using AKNA Polyclonal antibody (23785-1-AP)

    WB analysis of K-562 using 23785-1-AP (same clone as 23785-1-PBS)

    K-562 cells were subjected to SDS PAGE followed by western blot with 23785-1-AP (AKNA antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 23785-1-PBS in a different storage buffer formulation.

Product Information

23785-1-PBS targets AKNA in WB, Indirect ELISA applications and shows reactivity with human samples.

Tested Reactivity human
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen AKNA fusion protein Ag20662
Full Name AT-hook transcription factor
Calculated Molecular Weight 155 kDa
Observed Molecular Weight 65-70 kDa
GenBank Accession NumberBC055285
Gene Symbol AKNA
Gene ID (NCBI) 80709
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen Affinity purified
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

AKNA also named as AT hook transcription factor is a 1439 amino-acids protein. AKNA, encodes a lymphoid-specific AT-hook transcription factor that is highly expressed by B and T lymphocytes. It coordinately regulates expression of the CD40 receptor and its ligand (CD154), two molecules that are critical for antigen-dependent B-cell development. AKNA expresses at least nine distinct transcripts, some of which are expressed in a tissue-specific manner. These transcripts are products of alternative splicing, alternative promoter usage, and alternative polyadenylation. The alternative AKNA transcripts are predicted to encode overlapping protein isoforms, some of which (p70 and p100) (PMID:15869410)