AGXT2L1 Polyclonal antibody, PBS Only

AGXT2L1 Polyclonal Antibody for WB, IHC, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

WB, IHC, Indirect ELISA

Conjugate

Unconjugated

Cat no : 17042-1-PBS

Synonyms

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Validation Data Gallery

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  WB analysis using 17042-1-AP (same clone as 17042-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 17042-1-AP (AGXT2L1 antibody) at dilution of 1:6000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 17042-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse liver using 17042-1-AP (same clone as 17042-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse liver tissue slide using 17042-1-AP (AGXT2L1 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 17042-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse brain using 17042-1-AP (same clone as 17042-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 17042-1-AP (AGXT2L1 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 17042-1-PBS in a different storage buffer formulation.

• 

  IHC staining of mouse brain using 17042-1-AP (same clone as 17042-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 17042-1-AP (AGXT2L1 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 17042-1-PBS in a different storage buffer formulation.

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Product Information

17042-1-PBS targets AGXT2L1 in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse samples.

• Tested Reactivity: human, mouse
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen: AGXT2L1 fusion protein Ag10584
• Full Name: alanine-glyoxylate aminotransferase 2-like 1
• Calculated Molecular Weight: 499 aa, 56 kDa
• Observed Molecular Weight: 50-55 kDa
• GenBank Accession Number: BC022526
• Gene Symbol: AGXT2L1
• Gene ID (NCBI): 64850
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• Storage Buffer: PBS Only
• Storage Conditions: Store at -80°C.

Background Information

Alanine-glyoxylate aminotransferase 2-like 1 (AGXT2L1), also called ethanolamine phosphate phospholyase (ETNPPL), is a brain enzyme, so-named after its similarity to AGXT2 (36% sequence identity), that may be involved in the pathogenesis of severe neuropsychiatric disturbances(PMID: 23761375). AGXT2L1 is significantly down-regulated in cancerous tissues and may be a tumor suppressor(PMID: 26294768, 32724374).