AGGF1 Recombinant antibody, PBS Only

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  WB analysis using 84715-3-RR (same clone as 84715-3-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 84715-3-RR (AGGF1 antibody) at dilution of 1:4000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84715-3-PBS in a different storage buffer formulation.

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  Affinity and Kinetic Characterization of 84715-3-RR

  Biolayer interferometry (BLl) kinetic assays of 84715-3-RR against Human AGGF1 were performed. The affinity constant is below 1 pM.

AGGF1 Uni-rAb^TM Recombinant Antibody for WB, Indirect ELISA

Cat No. 84715-3-PBS

Clone No.242264E9

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, Indirect ELISA

Synonyms

HSU84971, GPATCH7, GPATC7, G patch domain-containing protein 7, Angiogenic factor VG5Q

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Product Information

84715-3-PBS targets AGGF1 in WB, Indirect ELISA applications and shows reactivity with human samples.

• Tested Reactivity: human
• Host / Isotype: Rabbit / IgG
• Class: Recombinant
• Type: Antibody
• Immunogen: AGGF1 fusion protein Ag2497
• Full Name: angiogenic factor with G patch and FHA domains 1
• Calculated Molecular Weight: 714 aa, 81 kDa
• Observed Molecular Weight: 84-100 kDa
• GenBank Accession Number: BC029382
• Gene Symbol: AGGF1
• Gene ID (NCBI): 55109
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purfication
• UNIPROT ID: Q8N302
• Storage Buffer: PBS Only
• Storage Conditions: Store at -80°C.

Background Information

The angiogenic factor gene, AGGF1 (or VG5Q), is identified as a candidate susceptibility gene for Klippel-Trenaunay syndrome (KTS) which is a severe congenital disorder characterized by capillary malformations, venous malformations or varicose veins, and hypertrophy of the affected tissues. AGGF1 protein can bind to endothelial cells and promote cell proliferation. AGGF1 shows strong expression in blood vessels and is secreted as vessel formation is initiated. Regulation of AGGF1 by GATA1 may play roles in endothelial cell biology and angiogenesis.