Product Information
60340-1-PBS targets Perilipin-2 in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.
Tested Reactivity | human, mouse, rat |
Host / Isotype | Mouse / IgG1 |
Class | Monoclonal |
Type | Antibody |
Immunogen | Perilipin-2 fusion protein Ag7643 Predict reactive species |
Full Name | adipose differentiation-related protein |
Calculated Molecular Weight | 48 kDa |
Observed Molecular Weight | 47-52 kDa |
GenBank Accession Number | BC005127 |
Gene Symbol | Perilipin-2 |
Gene ID (NCBI) | 123 |
RRID | AB_2881449 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purification |
UNIPROT ID | Q99541 |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. |
Background Information
ADRP (adipocyte differentiation related protein) also known as ADFP, adipophilin, or perilipin-2, is a member of PAT family which is responsible for the transportation of lipids and the formation of lipid droplets. ADRP is localized on the surface of lipid droplets in a variety of tissues and cell lines. ADRP is not detected in undifferentiated cells but increases rapidly to high levels when adipocyte precursors differentiate into adipocytes. Anti-ADRP antibody is a reliable and sensitive marker for lipid droplet. Enhanced expression of ADRP is linked to diseases with abnormal lipid storage, including hepatic steatosis, atherosclerosis and diabetes. Immunohistochemistry of ADRP may facilitate histomorphological diagnosis of these diseases.