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ADRB3 Polyclonal antibody, PBS Only

ADRB3 Polyclonal Antibody for WB, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, Indirect ELISA

Conjugate

Unconjugated

Cat no : 30713-1-PBS

Synonyms

Validation Data Gallery

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  • Western Blot (WB) analysis of various lysates using ADRB3 Polyclonal antibody (30713-1-AP)

    WB analysis using 30713-1-AP (same clone as 30713-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 30713-1-AP (ADRB3 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 30713-1-PBS in a different storage buffer formulation.

Product Information

30713-1-PBS targets ADRB3 in WB, Indirect ELISA applications and shows reactivity with human samples.

Tested Reactivity human
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen ADRB3 fusion protein Ag31466
Full Name adrenergic, beta-3-, receptor
Calculated Molecular Weight 44 kDa
Observed Molecular Weight44-50 kDa
GenBank Accession NumberNM_000025
Gene Symbol ADRB3
Gene ID (NCBI) 155
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

Beta-3 adrenergic receptor(ADRB3), a member of the G-protein-coupled receptor family, is expressed mainly in adipose tissue and is thought to contribute to lipolysis and thermogenesis. In addition, the overexpression of ADRB3 has been found in several cancer types, including breast cancer, gallbladder cancer , and colorectal cancer. More recently, the involvement of ADRB3 in the metabolic reprogramming of melanoma, the promotion of immune tolerance, and the regulation of cancer differentiation have been described. (PMID: 32514619)