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Adiponectin Recombinant antibody, PBS Only

Adiponectin Uni-rAbTM Recombinant Antibody for WB, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

241082C6

Cat no : 83961-4-PBS

Synonyms

ADIPOQ, ADIPQTL1, Adipocyte, C1q and collagen domain-containing protein, Adipocyte complement-related 30 kDa protein, 30 kDa adipocyte complement-related protein

Validation Data Gallery

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  • Western Blot (WB) analysis of various lysates using Adiponectin Recombinant antibody (83961-4-RR)

    WB analysis using 83961-4-RR (same clone as 83961-4-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 83961-4-RR (Adiponectin antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 83961-4-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 83961-4-RR

    Affinity and Kinetic Characterization of 83961-4-RR

    Biolayer interferometry (BLl) kinetic assays of 83961-4-RR against Human ADIPOQ were performed. The affinity constant is below 1 pM.

Product Information

The immunogen of 83961-4-PBS is Adiponectin Fusion Protein expressed in E. coli.

Tested Reactivity human
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Immunogen Adiponectin fusion protein Ag16304
Full Name adiponectin, C1Q and collagen domain containing
Calculated Molecular Weight 244 aa, 26 kDa
Observed Molecular Weight29 kDa
GenBank Accession NumberBC096308
Gene Symbol Adiponectin
Gene ID (NCBI) 9370
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purfication
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

Adiponectin (AdipoQ), an adipocyte-derived hormone, is one of the most abundant adipokines in the blood circulation. Adiponectin modulates a number of metabolic processes, including improving INS sensitivity and anti-inflammatory activity. The role of AdipoQ in reproduction is not yet fully understood, but the expression of AdipoQ in reproductive tissues has been observed in various animals and humans, including chicken testis, bovine ovary, and human placenta. Adiponectin exerts its effects by activating a range of different signaling molecules via binding to two transmembrane AdipoQ receptors, AdipoR1 and AdipoR2. AdipoR1 is expressed primarily in the skeletal muscle, whereas AdipoR2 is predominantly expressed in the liver. AdipoQ May play a role in cell growth, angiogenesis and tissue remodeling by binding and sequestering various growth factors.