ADC Monoclonal antibody, PBS Only
ADC Monoclonal Antibody for WB, IF/ICC, Indirect ELISA
Host / Isotype
Mouse / IgG1
Reactivity
Human, mouse, pig, rat
Applications
WB, IF/ICC, Indirect ELISA
Conjugate
Unconjugated
CloneNo.
1A2B11
Cat no : 67884-1-PBS
Synonyms
Validation Data Gallery
Product Information
67884-1-PBS targets ADC in WB, IF/ICC, Indirect ELISA applications and shows reactivity with Human, mouse, pig, rat samples.
Tested Reactivity | Human, mouse, pig, rat |
Host / Isotype | Mouse / IgG1 |
Class | Monoclonal |
Type | Antibody |
Immunogen | ADC fusion protein Ag31049 |
Full Name | arginine decarboxylase |
Calculated Molecular Weight | 460 aa, 50 kDa |
Observed Molecular Weight | 48-50 kDa |
GenBank Accession Number | BC028128 |
Gene Symbol | ADC |
Gene ID (NCBI) | 113451 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein G purification |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. |
Background Information
Antizyme inhibitor 2 (AZIN2) is a member of the antizyme inhibitor family, witch is able to bind to AZs and inhibit their action on both ODC activity and polyamine uptake. AZIN2 is predominantly expressed in the brain and testis and localized in the endoplasmic reticulum-golgi intermediate compartment. Available data suggest its role in cell growth, spermiogenesis, vesicular trafficking and secretion. Accumulation of azin2 has also been observed in brains of patients with Alzheimer's disease (PMID: 19832840) . AZIN2 has 5 described insoforms produced by alternative splicing. The molecular weight of AZIN2 is about 50 kDa.