ACVR1B Polyclonal antibody, PBS Only

• Featured Product
• KD/KO Validated

ACVR1B Polyclonal Antibody for WB, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, Indirect ELISA

Conjugate

Unconjugated

Cat no : 10086-1-PBS

Synonyms

---

Validation Data Gallery

• 

  WB analysis of HEK-293 using 10086-1-AP (same clone as 10086-1-PBS)

  HEK-293 cells were subjected to SDS PAGE followed by western blot with 10086-1-AP (ACVR1B Antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 10086-1-PBS in a different storage buffer formulation.

• 

  WB analysis of HepG2 using 10086-1-AP (same clone as 10086-1-PBS)

  DMSO treated HepG2 cells were subjected to SDS PAGE followed by western blot with 10086-1-AP (ACVR1B Antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 10086-1-PBS in a different storage buffer formulation.

---

Product Information

10086-1-PBS targets ACVR1B in WB, Indirect ELISA applications and shows reactivity with human samples.

• Tested Reactivity: human
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen: ACVR1B fusion protein Ag0129
• Full Name: activin A receptor, type IB
• Calculated Molecular Weight: 57 kDa
• Observed Molecular Weight: 50 kDa
• GenBank Accession Number: BC000254
• Gene Symbol: ACVR1B
• Gene ID (NCBI): 91
• RRID: AB_2877723
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• Storage Buffer: PBS Only
• Storage Conditions: Store at -80°C.

Background Information

ACVR1B (ALK4, activin A receptor type 1B) is a transforming growth factor-beta (TGF-beta) superfamily member (PMID: 37020544). A potential role for ACVR1B in regulating muscle mass is that it is part of the transforming growth factor b (TGFb) pathway regulating myostatin (PMID: 21063444).