ACMSD Polyclonal antibody, PBS Only

• 

  IHC staining of mouse kidney using 26834-1-AP (same clone as 26834-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse kidney tissue slide using 26834-1-AP (ACMSD antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 26834-1-PBS in a different storage buffer formulation.

• 

  IHC staining of mouse kidney using 26834-1-AP (same clone as 26834-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse kidney tissue slide using 26834-1-AP (ACMSD antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 26834-1-PBS in a different storage buffer formulation.

ACMSD Polyclonal Antibody for IHC, Indirect ELISA

Cat No. 26834-1-PBS

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

IHC, Indirect ELISA

Synonyms

---

Product Information

26834-1-PBS targets ACMSD in IHC, Indirect ELISA applications and shows reactivity with human, mouse samples.

• Tested Reactivity: human, mouse
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen: ACMSD fusion protein Ag25230
• Full Name: aminocarboxymuconate semialdehyde decarboxylase
• Calculated Molecular Weight: 38 kDa
• GenBank Accession Number: BC016018
• Gene Symbol: ACMSD
• Gene ID (NCBI): 130013
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• UNIPROT ID: Q8TDX5
• Storage Buffer: PBS Only
• Storage Conditions: Store at -80°C.

Background Information

ACMSD (alpha-amino-beta-carboxy-muconate-semialdehyde decarboxylase ) is the key enzyme that regulates the de novo NAD+ synthesis from tryptophan. ACMSD is highly expressed in the liver, kidney and to a lower degree in brain under physiological conditions. The enzyme is primarily cytosolic and is positioned at a critical branching point in the kynurenine pathway, wherein it influences the fate of the precursor 2-amino-3-carboxymuconic-6-semialdehyde (ACMS).