ABL2 Antibody 0 Publications

Mouse Monoclonal| Catalog number: 65041-1-Ig

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Freight/Packing

Size: 09µ/gram

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Tested Applications

Applications:
ELISA, WB
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Species specificity:
human

Positive WB detected in:
Human brain

Recommended dilution:
WB : 1:500-1:5000

Product Information


Source:
Mouse

Purification method:
Other

Isotype:
IgG1

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Immunogen:
Recombinant Protein

Full name:
v-abl Abelson murine leukemia viral oncogene homolog 2 (arg, Abelson-related gene)

Calculated molecular weight:
1167aa,127 kDa

Observed molecular weight:
128 kDa-140 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
ABL2

Synonyms
Abelson related gene protein, ABL2, ABLL, ARG, FLJ22224, FLJ31718, FLJ41441, Tyrosine protein kinase ABL2, Tyrosine protein kinase ARG
Background

ABL2(Abelson tyrosine-protein kinase 2) is also named as ABLL, ARG and belongs to the protein kinase superfamily. It is a membrane-anchored nonreceptor tyrosine kinase that is a novel mediator of SEMA3F-induced RhoA inactivation and collapsing activity and it has a role in cytoskeletal rearrangements by its C-terminal F-actin- and microtubule-binding sequences. ABL2 can be polyubiquitinated and the polyubiquitination of ABL2 leads to degradation. This protein has 9 isoforms produced by alternative splicing with the molecular weight from 114 kDa to 128 kDa. The antibody is specific to the others except the 60 kDa isoform of ABL2.


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