ABCD1 Monoclonal antibody, PBS Only

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  WB analysis of HeLa using 60153-1-Ig (same clone as 60153-1-PBS)

  WB result of ABCD1 antibody (60153-1-Ig, 1:1000) with si-Control and si-ABCD1 transfected HeLa cells. This data was developed using the same antibody clone with 60153-1-PBS in a different storage buffer formulation.

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  WB analysis of HeLa using 60153-1-Ig (same clone as 60153-1-PBS)

  HeLa cells were subjected to SDS PAGE followed by western blot with 60153-1-Ig (ABCD1 antibody) at dilution of 1:400 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 60153-1-PBS in a different storage buffer formulation.

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  IF Staining of HeLa using 60153-1-Ig (same clone as 60153-1-PBS)

  Immunofluorescent analysis of (-20°C Ethanol) fixed HeLa cells using ABCD1 antibody (60153-1-Ig, Clone: 1H8E5 ) at dilution of 1:100 and CoraLite®488-Conjugated Goat Anti-Mouse IgG(H+L).DAPI (blue). This data was developed using the same antibody clone with 60153-1-PBS in a different storage buffer formulation.

• Featured Product
• KD/KO Validated

ABCD1 Monoclonal Antibody for WB, IF/ICC, Indirect ELISA

Cat No. 60153-1-PBS

Host / Isotype

Mouse / IgG1

Reactivity

human

Applications

WB, IF/ICC, Indirect ELISA

Synonyms

ABC42, ABCD1, Adrenoleukodystrophy protein, ALD, ALDP, AMN

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Product Information

60153-1-PBS targets ABCD1 in WB, IF/ICC, Indirect ELISA applications and shows reactivity with human samples.

• Tested Reactivity: human
• Host / Isotype: Mouse / IgG1
• Class: Monoclonal
• Type: Antibody
• Immunogen: ABCD1 fusion protein Ag12757
• Full Name: ATP-binding cassette, sub-family D (ALD), member 1
• Calculated Molecular Weight: 745 aa, 83 kDa
• Observed Molecular Weight: 75 kDa
• GenBank Accession Number: BC025358
• Gene Symbol: ABCD1
• Gene ID (NCBI): 215
• RRID: AB_10640436
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purification
• UNIPROT ID: P33897
• Storage Buffer: PBS Only
• Storage Conditions: Store at -80°C.

Background Information

ABCD1 (also known as ALDP) is a member of the ATP-binding cassette (ABC) transporter superfamily which functions as transporter for a wide variety of substrates. It localizes to the peroxisomal membrane. The exact function is not clear so far. Various mutations of ABCD1 cause X-linked adrenoleukodystrophy (X-ALD), an inherited neurodegenerative disease affecting the nervous system white matter and adrenal cortex.