ABCA3 Recombinant antibody, PBS Only

ABCA3 Uni-rAb^TM Recombinant Antibody for Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

Indirect ELISA

Conjugate

Unconjugated

CloneNo.

230194C12

Cat no : 83018-1-PBS

Synonyms

ABC-C transporter, ABCA 3, ABC3, ABC C transporter, 230194C12

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Validation Data Gallery

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  Affinity and Kinetic Characterization of 83018-1-RR

  Biolayer interferometry (BLl) kinetic assays of 83018-1-RR against Human ABCA3 were performed. The affinity constant is 1.35 nM.

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Product Information

83018-1-PBS targets ABCA3 in Indirect ELISA applications and shows reactivity with human samples.

• Tested Reactivity: human
• Host / Isotype: Rabbit / IgG
• Class: Recombinant
• Type: Antibody
• Immunogen: ABCA3 fusion protein Ag24749
• Full Name: ATP-binding cassette, sub-family A (ABC1), member 3
• GenBank Accession Number: BC140895
• Gene Symbol: ABCA3
• Gene ID (NCBI): 21
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purification
• Storage Buffer: PBS Only
• Storage Conditions: Store at -80°C.

Background Information

ABCA3 belongs to the ATP-binding cassette (ABC) transporter superfamily. ABCA3, which is expressed in alveolar type II pneumocytes and localizes predominantly to the limiting membrane of lamellar bodies, is critical for synthesis of surfactant(PMID: 17267394). Mutation of the ABCA3 gene causes fatal surfactant deficiency in newborns(PMID: 15044640).